Scientists at the Scripps Research Institute in the United States found antibodies in the blood of patients who recovered from COVID-19 that provide powerful protection against coronavirus. This was reported in an article published in the journal Science.
Researchers took blood samples from people who had mild and severe forms of the disease. During the experiment, specialists used test cells synthesizing the ACE2 receptor, with which the virus interacts before it enters the cell. Scientists have tested whether antibody-containing blood can bind to the virus and block the infection process.
Experts have identified more than a thousand different antibody-producing immune cells called B cells, each of which synthesized a different type of antibody against SARS-CoV-2. When the sequence of genes encoding antibodies was established, scientists were able to synthesize them in the laboratory. Screening results showed that some antibodies, even in small amounts, could effectively block the virus, preventing the infection of test cells.
According to scientists, if further safety tests on animals and clinical trials involving humans are successful, then antibodies can be used as a therapeutic agent as early as January next year.